PBSerum Specific

Professional enzyme treatments for targeted skin concerns

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Designed for Professional Routines. Adapted to Your Skin.

What is PBSerum Specific?

PBSerum Specific is a professional-grade enzyme treatment designed to address specific skin concerns. Each product is tailored to target different skin issues, providing targeted solutions for improved skin health and appearance.

PBSerum Specific Products

PBSerum Specific products are designed to address specific skin concerns, providing targeted solutions for improved skin health and appearance.

Face

Face

facial rejuvenation

Hands

Hands

hands rejuvenation

Periocular

Periocular

eye area rejuvenation

Acne

Acne

treatment of post-acne scars

Striae

Striae

stretch mark correction

3 MAIN CAUSES OF SKIN AGING

1. Evolution of the Extracellular Matrix (ECM) Structure

Over time, collagen undergoes glycation and cross-linking, causing collagen fibrils to become thicker and less flexible. This structural change reduces skin elasticity and contributes to visible signs of aging.

2. Cellular Senescence

A decline in fibroblast growth factor (FGF) — which helps prevent cellular aging — leads to accelerated skin aging. Fibroblasts' metabolic activity decreases, and FGF is required to restore their function and maintain skin vitality.

3. Photoaging and Oxidative Stress

An imbalance between reactive oxygen species (ROS) production and the skin's antioxidant defense leads to oxidative stress. This damage from UV exposure and environmental factors accelerates the aging process and impairs skin integrity.

PBserum SPECIFIC offers 3 UNIQUE SOLUTIONS to Key Skin Aging Problems:

1. Remodeling of the Extracellular Matrix (ECM)

Collagenase G & H

Break down disorganized collagen in scarred and fibrotic tissues, removing fibrosis and promoting tissue reorganization. This process supports the synthesis of new, properly structured collagen, improving skin architecture.

2. Release of Trophic Factors to Activate Fibroblasts

PB72K Lyase

Stimulates fibroblast activity, enhancing the production of collagen, elastin, and hyaluronic acid. Growth factors that are trapped within the ECM are released, accelerating tissue repair and regeneration.

3. Photoaging Correction

Antioxidants and Retinoids

Protect the skin from oxidative stress and shield the extracellular matrix. Retinoids promote cell turnover, increase the synthesis of collagen and elastin, and improve overall skin texture and tone.

PROFESSIONAL LINE + HOME CARE ROUTINE

5 Professional-grade products and 5 complementary home-care formulas to achieve maximum results through a comprehensive treatment approach.

PROFESSIONAL LINE

Formula enriched with enzyme systems + active ingredients:

  • Enzymes: Collagenase, Lyase
  • Vitamins: A, C, E
  • Other actives: Ferulic Acid, Niacinamide, Zinc Sulfate, Melatonin, DMAE, Tranexamic Acid, Allantoin

Designed for in-clinic use to deliver intensive, targeted action for skin regeneration, anti-aging, brightening, and restructuring.

HOME CARE LINE

Formula with enzymes + active ingredients for daily support:

  • Enzymes: Keratinase, Collagenase
  • Vitamins: A, C, E
  • Other actives: Kojic Acid, Carnosine, DMAE, Glycosaminoglycans, Alpinia Galanga Extract, Hyaluronic Acid

Optimized to maintain and prolong in-clinic results, supporting skin renewal, hydration, antioxidant defense, and pigmentation control.

face Professional Treatment

AGEDEFY FACE Prof

Active Ingredients:

Collagenase GH PB220, Lyase PB72K

Indications:

  • Expression lines (mimic wrinkles)
  • Uneven skin tone
  • Facial skin laxity
  • Overall skin appearance improvement

Packaging Format:

Box contains:

3 vials of lyophilized powder + 3 vials of solvent

Collagenase enzyme

COLLAGENASE G/H PB220

Promotes the regeneration and reorganization of collagen fibers in the dermis.

Improves skin texture and appearance, enhancing elasticity and firmness through a powerful lifting effect.

Keratinase enzyme

KERATINASE PB333

Utilizing selective enzyme technology, it supports cell renewal and provides gentle yet effective exfoliation without causing irritation or breakouts.

Increases skin permeability, improving the absorption of other active ingredients.

Lyase enzyme

LYASE PB72K

Enhances tissue permeability and boosts the penetration of collagenase and lipase.

Breaks down molecules responsible for fluid and toxin retention in the extracellular matrix, helping to reduce body volume and improve skin appearance.

Results BEFORE and AFTER application of PBserum "Specific" products

Before face treatment 1
After face treatment 1
Before
After

Dr. Sandra De Oliveira

Face - 3 sessions

Before face treatment 2
After face treatment 2
Before
After

Dr Beatrice Martin

Face - 3 sessions

Before face treatment 3
After face treatment 3
Before
After

Dr. Sandra De Oliveira

Striae - 4 sessions

Before face treatment 4
After face treatment 4
Before
After

Dr. Nikolaus Ducek

Striae - 4 sessions

Before body treatment 7
After body treatment 7
Before
After

Dr. Sandra De Oliveira

Acne Scars - 4 sessions

Before body treatment 8
After body treatment 8
Before
After

Dr. Melania Batistella

Hands - 3 sessions

Before body treatment 9
After body treatment 9
Before
After

Dr. Nikolaus Ducek

Face - 3 sessions

Before body treatment 9
After body treatment 9
Before
After

Acne Scars

4 sessions

Use in Combination with Cosmetic Devices and Equipment

It is not recommended to use any device immediately after applying the product. Each enzyme has an optimal temperature and pH range depending on its function. PBserum enzymes are designed to function at normal physiological conditions.

To avoid enzyme denaturation, follow these guidelines based on the type of device:

1. Devices that generate heat (e.g., radiofrequency, ultrasound, laser):

  • Use at least 30 minutes before enzyme application,
  • or schedule device-based treatments between enzyme sessions.

2. Devices that cool tissues (e.g., cryotherapy):

  • Wait at least 7 days before or after enzyme application.